Aneuploidy screening in the first trimester
نویسندگان
چکیده
منابع مشابه
Aneuploidy screening in the first trimester.
This article reviews the performance of first trimester screening for chromosomal anomalies using various combinations of ultrasound and maternal serum biochemical modalities. Detection rates in excess of 90% can be routinely achieved for Trisomy 21, Trisomy 13, Trisomy 18 using a combination of fetal nuchal translucency (NT) thickness and maternal serum free ss-hCG and PAPP-A at 11 + 0 to 13 +...
متن کاملFirst trimester aneuploidy screening in the presence of a vanishing twin: implications for maternal serum markers.
OBJECTIVE To assess the impact of a vanishing twin on the levels of the biochemical markers used in the first trimester aneuploidy screening. METHODS A retrospective analysis of free beta-hCG and PAPP-A levels in 270 women with a normal singleton fetus with ultrasound evidence of a vanishing twin pregnancy. Marker levels (as MoM) were compared in three groups-76 women with a second empty gest...
متن کاملFirst Trimester Aneuploidy Screening Program for Preeclampsia Prediction in a Portuguese Obstetric Population
Objective. To evaluate the performance of a first trimester aneuploidy screening program for preeclampsia (PE) prediction in a Portuguese obstetric population, when performed under routine clinical conditions. Materials and Methods. Retrospective cohort study of 5672 pregnant women who underwent routine first trimester aneuploidy screening in a Portuguese university hospital from January 2009 t...
متن کاملEarly vaginal bleeding has no impact on markers used in first trimester aneuploidy screening.
OBJECTIVE To assess the impact of early vaginal bleeding on the levels of markers used in first trimester screening for aneuploidy. METHODS A retrospective analysis was carried out on the free beta human chorionic gonadotrophin (beta-hCG) and pregnancy associated plasma protein-A (PAPP-A) levels and nuchal translucency thickness in 49 653 women with a normal singleton fetus who had first trim...
متن کاملFirst Trimester Aneuploidy Screening Markers in Women with Pre-Gestational Diabetes Mellitus
OBJECTIVE To investigate whether maternal serum pregnancy associated plasma protein-A (PAPP-A), total β human chorionic gonadotropin (hCG) levels and nuchal translucency (NT) measurements differ in women with pre-gestational diabetes mellitus (PGDM) compared to non-diabetic controls and to assess whether correction factors are needed for diabetic women in calculation of aneuploidy risks. STUD...
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ژورنال
عنوان ژورنال: American Journal of Medical Genetics Part C: Seminars in Medical Genetics
سال: 2007
ISSN: 1552-4868,1552-4876
DOI: 10.1002/ajmg.c.30119